Naomi Cotton
Papers
1
Total Citations
57
H-Index
1
About
Naomi Cotton is a chemical biologist whose work bridges the gap between high-throughput screening and eukaryotic cell biology. Her research focuses on developing innovative assay platforms to accelerate the discovery of biologically active small molecules, with a particular emphasis on leveraging the budding yeast *Saccharomyces cerevisiae* as a model system. Cotton’s most notable contribution is the development of a high-throughput yeast halo assay, detailed in her highly cited 2007 paper (57 citations), which enables rapid, automated toxicity screening of compound libraries. This work has provided researchers with a powerful, cost-effective tool for identifying bioactive compounds that can modulate fundamental eukaryotic processes, from cell cycle regulation to stress responses. By streamlining the discovery pipeline, Cotton’s methodology has had a lasting impact on both basic cell biology research and early-stage drug development, offering a scalable approach to probe complex biological pathways. Her achievements exemplify how creative assay design can transform model organisms into engines for chemical discovery, making her a key figure in the field of chemical genetics.
Research Focus
Key Achievements
Top Papers
- 1