Anand K. Ramasubramanian

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About

Anand K. Ramasubramanian is a biomedical engineer and microfluidics innovator whose research sits at the intersection of microtechnology, infectious disease, and drug discovery. His most recognized contribution is the pioneering development of the *Candida albicans* Biofilm Chip (CaBChip), a high-throughput microarray platform capable of growing nanoscale fungal biofilms on surface-modified microscope slides using robotic printing technology. By encapsulating yeast cells in collagen matrices at volumes as low as 50 nanoliters, Ramasubramanian's team created a transformative tool for studying *Candida albicans*—the primary cause of candidiasis and the fourth most common nosocomial bloodstream infection in U.S. hospitals. This platform, detailed in his most-cited work (47 citations), directly enables accelerated antifungal drug screening, a critical need given the rising threat of drug-resistant fungal infections in immunocompromised patients. His subsequent refinement of the CaBChip for high-throughput antifungal screening further demonstrates his commitment to translating engineering innovation into clinically relevant solutions. Ramasubramanian's work represents a meaningful advance in combating life-threatening opportunistic fungal infections through miniaturized, scalable biofilm technology.