Craig M. Tamble
Papers
1
Total Citations
57
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1
About
Craig M. Tamble is a chemical biologist whose work bridges the gap between high-throughput screening and eukaryotic cell biology. His research centers on developing innovative assays to accelerate the discovery of biologically active small molecules, with a particular focus on leveraging the budding yeast *Saccharomyces cerevisiae* as a model system. Tamble’s most notable contribution is the creation of a high-throughput yeast halo assay, a novel toxicity screen that is both easily automatable and highly compatible with large-scale drug discovery efforts. This work, published in 2007 and cited 57 times, has provided researchers with a powerful and efficient tool for identifying compounds that disrupt fundamental eukaryotic cellular processes. By enabling the rapid screening of vast chemical libraries, Tamble’s methodology has significantly streamlined the path from initial hit to potential therapeutic lead. His achievements underscore a commitment to practical, scalable solutions in chemical genetics, making his research a valuable resource for students and scientists exploring the intersection of cell biology and drug development.
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