Michael Platchek

Institute of Medical Cell Technologies, AM Technologies (Poland)

Papers

Total Citations

H-Index

About

Michael Platchek is a researcher specializing in cell-based assay development and high-throughput screening (HTS) technologies. His work has focused on solving one of the most persistent challenges in pharmaceutical drug discovery: achieving consistent, reproducible results in large-scale cell-based screening operations. Platchek's most significant contribution lies in the development and application of Division Arrest Technology, a method designed to standardize cell quality for high-throughput screening. His landmark 2005 paper, "Application of Division Arrest Technology to Cell-Based HTS," which has garnered 33 citations, demonstrated how division-arrested cells compare favorably to both frozen and fresh cells in functional assays — offering a practical solution for laboratories requiring reliable cell supply over extended screening campaigns. Complementing this work, his second key publication explores how division-arrested cells improve day-to-day assay consistency, addressing the variability inherent in using live biological reagents across robotic screening platforms. Together, these contributions — accumulating 50 citations — have helped advance the reliability and scalability of cell-based HTS methods during a pivotal period when automation and detection technologies were rapidly transforming drug discovery workflows. His research remains relevant to scientists designing robust, reproducible screening pipelines in both academic and industrial settings.