Mei Cong

Institute of Medical Cell Technologies, AM Technologies (Poland)

Papers

Total Citations

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About

Mei Cong is a researcher specializing in cell-based high-throughput screening (HTS) and assay development, with a particular focus on optimizing cellular reagents for large-scale drug discovery applications. Her most significant contribution lies in pioneering the application of division arrest technology to cell-based assays, a methodological advance that addressed one of the field's most persistent challenges: maintaining consistent, reproducible cellular responses across extended screening campaigns. Cong's landmark 2005 research demonstrated that division-arrested cells — prepared using low-level mitomycin C treatment — outperform both fresh and frozen cell preparations in terms of consistency and quality, making them far more reliable as reagents in robotic screening environments. This body of work, spanning functional HTS assays and high-content screening platforms, earned a combined total of approximately 60 citations and has meaningfully influenced how HTS laboratories approach cell supply and standardization. Her research directly addressed the operational realities of industrial-scale drug screening, where day-to-day variability in cellular response can compromise entire compound libraries. By establishing division-arrested cells as a viable and superior alternative, Cong helped lay practical groundwork for more reproducible and efficient early-stage drug discovery workflows.