Natalie Fursov

Cellular Research (United States), AM Technologies (Poland)

Papers

Total Citations

H-Index

About

Natalie Fursov is a researcher specializing in cell-based assay development and high-throughput screening (HTS) methodologies, with particular expertise in improving the consistency and reliability of cellular reagents used in drug discovery workflows. Her most recognized contributions center on the innovative application of division-arrested cells to address one of the most persistent challenges in automated screening: biological variability in cell populations. In her 2005 publications, Fursov and colleagues demonstrated that treating cells with low-level mitomycin C to arrest cell division could substantially enhance the reproducibility of both standard cell-based assays and high-content screening platforms — a meaningful advancement for robotic HTS environments where consistency is paramount. By reframing cells themselves as critical, controllable reagents rather than passive experimental tools, her work offered practical strategies that laboratories could adopt to strengthen screening data quality. With a combined citation count of 27 across her two most prominent papers, Fursov's research has contributed meaningfully to the fields of cell biology and pharmaceutical screening technology. Her work remains relevant to scientists and drug discovery teams seeking to reduce assay noise and improve the translational value of high-throughput compound screening campaigns.