Marius Busche
Papers
1
Total Citations
19
H-Index
1
About
Marius Busche is a leading figure in microfluidic organ-on-chip engineering, with a core focus on developing advanced in vitro liver models for drug testing and toxicology. His most notable contribution is the HepaChip-MP, a groundbreaking twenty-four chamber microplate that enables continuously perfused liver coculture. This platform uses automated dielectrophoresis to selectively assemble viable primary human cells into elongated microtissues, creating a more physiologically relevant environment than static culture systems. The HepaChip-MP, detailed in his 2020 paper with 19 citations, represents a significant step toward high-throughput, reproducible liver models that better predict in vivo drug responses. Busche’s work bridges microfluidics, tissue engineering, and hepatology, offering a powerful tool for reducing animal testing and improving preclinical drug screening. His innovations in microtissue assembly and perfusion technology have positioned him as an emerging authority in the field, with his research directly impacting the design of next-generation organ-on-a-chip platforms for personalized medicine and pharmaceutical development.
Research Focus
Key Achievements
Top Papers
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