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About

Jeremy L. Praissman is a structural biologist whose work has significantly advanced high-throughput protein crystallography. His key research areas include structural genomics, protein engineering, and automated crystallographic pipelines. Praissman’s major contribution lies in his role at the Southeast Collaboratory for Structural Genomics (SECSG), where he helped develop an integrated, robot-driven pipeline that streamlined the entire process from protein expression to structure determination. This work, detailed in his highly cited 2005 paper "The high-throughput protein-to-structure pipeline at SECSG" (24 citations), demonstrated how automation could dramatically accelerate structural biology, enabling the rapid characterization of proteins on a genomic scale. By integrating robotics for cloning, expression, purification, and crystallization, Praissman’s pipeline reduced manual labor and increased throughput, setting a standard for structural genomics initiatives. His achievements underscore the power of automation in solving protein structures efficiently, making him a notable figure in the push toward high-throughput structural biology. For students and researchers, Praissman’s work exemplifies how engineering and biology converge to unlock the molecular machinery of life at unprecedented speed.