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About

Jane S. Richardson is a pioneering structural biologist whose work has fundamentally shaped our understanding of protein architecture. Her key research areas include macromolecular crystallography, protein structure validation, and the development of computational tools for structural biology. Richardson is best known for creating the Richardson diagram, or "ribbon diagram," a now-ubiquitous method for visualizing protein backbone structures that revolutionized how scientists communicate complex molecular shapes. She also co-developed the MolProbity web service, a critical tool for validating and improving protein structures, which is used by thousands of researchers worldwide and has been cited over 5,000 times. Her contributions to high-throughput structural genomics, exemplified by the Southeast Collaboratory for Structural Genomics (SECSG) pipeline, have enabled rapid protein structure determination with automated methods. Richardson's work has earned her numerous honors, including election to the National Academy of Sciences and the Protein Society's Stein & Moore Award. Her legacy endures in every ribbon diagram drawn and every validated protein structure deposited in the PDB.