J.K. Everett
Papers
1
Total Citations
130
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1
About
J.K. Everett is a structural biologist whose work has been central to advancing high-throughput protein production and structural genomics. As a key contributor to the Northeast Structural Genomics Consortium (NESG), Everett developed and implemented a robotic cloning and protein production platform that streamlined the expression and purification of thousands of proteins for structural determination. This seminal 2005 paper, cited over 130 times, established a scalable pipeline that became a gold standard for large-scale structural biology projects, enabling the rapid characterization of novel protein folds and functions. Everett’s innovations reduced manual labor and increased reproducibility, directly impacting the efficiency of the Protein Structure Initiative. Their work has been instrumental in bridging the gap between genomic sequence data and three-dimensional protein structures, facilitating discoveries in enzyme catalysis, signaling, and drug target identification. By creating automated workflows that integrated cloning, expression testing, and purification, Everett helped democratize structural biology, making it accessible to larger consortia and individual labs alike. Their contributions remain foundational for modern proteomics and structural genomics research.
Research Focus
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