Holger Becker
Papers
1
Total Citations
19
H-Index
1
About
Dr. Holger Becker is a pioneering figure in microfluidics and organ-on-a-chip technology, with a focus on developing advanced in vitro models for drug testing and toxicology. His key research areas include microfluidic cell culture platforms, dielectrophoresis-based cell manipulation, and liver tissue engineering. Dr. Becker's major contribution is the development of the HepaChip-MP, a groundbreaking twenty-four chamber microplate that enables continuous, unidirectional perfusion of liver cocultures. This system uses automated dielectrophoresis to selectively assemble viable primary human hepatocytes into elongated microtissues, mimicking in vivo liver architecture and function. With his most-cited paper accumulating 19 citations, Dr. Becker's work addresses a critical need for more physiologically relevant models in pharmaceutical research. His notable achievement includes creating a platform that maintains liver-specific functions over extended periods, offering a promising alternative to traditional 2D cultures and animal testing. Dr. Becker's innovations are instrumental in advancing personalized medicine and reducing drug development costs, making him a key contributor to the future of biomedical engineering.
Research Focus
Key Achievements
Top Papers
- 1