Hirotaka Sugiura
Papers
6
Total Citations
60
H-Index
3
About
Hirotaka Sugiura is a pioneering researcher at the intersection of microfluidics, robotics, and cellular biomechanics, whose work has significantly advanced the precision measurement and manipulation of biological cells at the microscale. He is best known for developing robot-integrated microfluidic chips — sophisticated "robochips" — that enable automated, high-throughput mechanical characterization of single cells. His landmark 2015 paper introducing a Moiré fringe-based on-chip method to quantify cellular mechanical properties has garnered 36 citations, establishing him as an innovator in cell elasticity measurement. Sugiura subsequently expanded this framework with large-indentation techniques, improving accuracy in determining cell stiffness parameters. More recently, his research has turned toward the automated handling of oocytes, particularly Xenopus oocytes, developing robotic capillary insertion systems, movable microfluidic chips exploiting gap effects, and novel pipette-tip microsensors fabricated through combined 3D printing and MEMS processes. These contributions collectively address longstanding challenges in reproducible, single-cell manipulation for electrophysiology and molecular biology applications. With a growing body of work spanning cell mechanics, biosensing, and robotic micromanipulation, Sugiura represents an important voice in the emerging field of intelligent biomedical microsystems.
Research Focus
Key Achievements
Top Papers
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- 6A Movable Microfluidic Chip with Gap Effect for Manipulation of Oocytes3 citations · 2024