Yoav Peleg
Papers
2
Total Citations
15
H-Index
2
About
Yoav Peleg is a structural biologist whose work bridges fundamental molecular architecture and human health. A key figure at the Israel Structural Proteomics Center (ISPC), Peleg’s research focuses on determining the three-dimensional structures of proteins relevant to human disease, with a particular emphasis on capturing these molecules in their functional context—often complexed with natural partner proteins or DNA. This approach provides critical insights into biological mechanisms and potential therapeutic targets. Among his notable contributions is the crystal structure determination of YagE, a putative DHDPS-like protein from *Escherichia coli K12*. This work sheds light on how bacteriophage-mediated genetic transfer can introduce novel proteins into bacterial genomes, potentially contributing to drug resistance or pathogenicity. While his most cited paper (10 citations) establishes the foundational mission of the ISPC, Peleg’s broader impact lies in advancing the structural understanding of proteins that underpin both normal physiology and disease, offering a molecular lens through which to view infection, immunity, and cellular regulation.
Research Focus
Key Achievements
Top Papers
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