Tamar Unger
Papers
2
Total Citations
15
H-Index
2
About
Tamar Unger is a structural biologist whose work bridges fundamental protein science and human health. Her research centers on the three-dimensional structure determination of proteins, with a particular emphasis on those implicated in disease and their functional interactions. As a key contributor to the Israel Structural Proteomics Center (ISPC), Unger has advanced the field by focusing not just on isolated proteins, but on complexes with their natural partners—including other proteins and DNA—to capture biological context. Her most cited work, a 2005 study outlining the ISPC’s strategic approach, has garnered 10 citations and established a framework for high-throughput structural genomics targeting medically relevant targets. In a complementary study from 2008, she solved the crystal structure of YagE, a putative DHDPS-like protein from *E. coli K12*, shedding light on how bacteriophage-mediated gene transfer can introduce novel proteins into bacterial genomes—a process with implications for understanding drug resistance and pathogenicity. Through these contributions, Unger has demonstrated how structural biology can reveal both the architecture of health-related proteins and the evolutionary mechanisms that shape bacterial virulence.
Research Focus
Key Achievements
Top Papers
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