Shira Albeck
Papers
2
Total Citations
15
H-Index
2
About
Shira Albeck is a structural biologist whose work illuminates the molecular machinery of life, with a particular focus on proteins relevant to human health. As a key member of the Israel Structural Proteomics Center (ISPC), Albeck has been instrumental in advancing the high-throughput determination of three-dimensional protein structures in their functional contexts. Her landmark 2005 paper (10 citations) outlines the center’s ambitious goal: solving the structures of proteins complexed with their natural partners—other proteins or DNA—to understand their roles in disease and health. This work provides a critical foundation for rational drug design and mechanistic biology. Albeck also contributed to the structural characterization of YagE, a putative DHDPS-like protein from *Escherichia coli K12* (2008, 5 citations), a study that explores how bacteriophage integration can introduce novel genes, potentially conferring drug resistance or pathogenicity. By determining the crystal structure of such proteins, Albeck helps reveal how horizontal gene transfer shapes bacterial evolution. Her research sits at the intersection of structural genomics, microbiology, and medicine, offering essential insights into the molecular basis of health and disease.
Research Focus
Key Achievements
Top Papers
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