Sophie Perrier
Papers
1
Total Citations
80
H-Index
1
About
Sophie Perrier is a structural biologist whose pioneering work in medium-throughput crystallization has significantly advanced the field of structural genomics. Her landmark 2002 paper, with 80 citations, introduced a groundbreaking two-step crystallization approach that combines large-scale robotic screening with manual or automated optimization—a methodology that has become a cornerstone for laboratories worldwide seeking to accelerate protein structure determination. By demonstrating the practical value of this hybrid strategy, Perrier effectively bridged the gap between high-throughput automation and the nuanced art of crystallization, enabling researchers to tackle previously intractable targets. Her contributions have not only streamlined the process of obtaining diffraction-quality crystals but have also laid the groundwork for modern structural genomics initiatives. Perrier’s work continues to inspire new generations of structural biologists, offering a pragmatic yet innovative framework that balances efficiency with precision—a testament to her lasting impact on how we visualize the molecular machinery of life.
Research Focus
Key Achievements
Top Papers
- 1A medium-throughput crystallization approach80 citations · 2002