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About

Fabienne Pagot is a structural biologist whose pioneering work in medium-throughput crystallization has significantly advanced the field of structural genomics. Her most cited research, "A medium-throughput crystallization approach" (2002, 80 citations), established a foundational two-step procedure that combines large-scale robotic screening with manual or automated optimization of crystallization conditions. This innovative methodology demonstrated the practical value of balancing efficiency and precision, enabling researchers to tackle protein structures at a scale previously unattainable. Pagot's contributions have been instrumental in streamlining the path from gene to structure, reducing bottlenecks in protein crystallography and accelerating the discovery of novel biological mechanisms. Her work remains a cornerstone for laboratories seeking to implement cost-effective, high-yield crystallization pipelines, influencing both academic research and pharmaceutical development. Through her strategic integration of automation and expert refinement, Pagot has left a lasting impact on how structural biology projects are designed and executed, making her a key figure in the evolution of modern crystallographic approaches.