Salman R. Khetani
Papers
2
Total Citations
34
H-Index
2
About
Dr. Salman R. Khetani is a leading figure in hepatic tissue engineering, whose work bridges materials science and stem cell biology to create advanced liver models. His research focuses on how the liver’s microenvironment—specifically the extracellular matrix (ECM) and mechanical stiffness—controls the behavior of human hepatocytes. In a landmark 2021 study (13 citations), Dr. Khetani used protein microarrays to systematically reveal how ECM composition and stiffness cooperatively regulate primary human hepatocyte attachment and function at single-cell resolution. He then extended this approach to human iPSC-derived hepatocytes in a 2022 paper (21 citations), demonstrating how ECM microarrays can modulate and improve the phenotype of these stem cell-derived cells for drug screening and disease modeling. By providing a high-throughput platform to decode the liver’s niche, Dr. Khetani’s work has major implications for regenerative medicine and toxicology. His innovative use of cell microarrays and high-content imaging has established a new paradigm for understanding how physical and biochemical cues govern liver cell fate, earning him recognition as a pioneer in precision hepatocyte culture.
Research Focus
Key Achievements
Top Papers
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