Rangana Warshamanage
Papers
1
Total Citations
98
H-Index
1
About
Rangana Warshamanage is a structural biologist whose research centers on advancing X-ray crystallographic methods for protein structure determination, with a particular focus on membrane proteins and challenging biological targets. Their most notable contribution is the development of an innovative *in meso in situ* serial X-ray crystallography technique, published in 2015 and cited nearly 100 times. This method enables the direct diffraction data collection from crystals growing in lipid cubic or sponge phases at cryogenic temperatures, elegantly bypassing the technically demanding and inefficient crystal-harvesting step that often plagues membrane protein studies. By streamlining the experimental workflow, Warshamanage’s work has made it significantly more accessible to determine high-resolution structures of both soluble and membrane proteins, which are critical for understanding cellular signaling and drug design. Their methodological innovation has been widely adopted by the structural biology community, demonstrating substantial impact in a field where technical bottlenecks frequently limit progress. This achievement underscores Warshamanage’s role in pushing the boundaries of crystallographic techniques, offering practical solutions that accelerate discovery in molecular biophysics.
Research Focus
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Top Papers
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