P. McQuary

Papers

Total Citations

328

H-Index

About

P. McQuary is a pioneering figure in the development of high-throughput bioanalytical platforms, with a primary focus on advancing immunoassay technologies. Their most impactful contribution is the creation of a novel biochip for multiplexed enzyme-linked immunosorbent assays (ELISAs), detailed in their landmark 1999 paper, which has garnered 328 citations. This innovation, featuring an optically flat glass plate with 96 wells defined by a hydrophobic Teflon mask, dramatically increased the efficiency and scalability of protein detection. By enabling simultaneous, high-throughput analysis, McQuary’s work laid critical groundwork for modern proteomics and clinical diagnostics. Their research has been instrumental in transforming traditional ELISA methods into robust, array-based systems, reducing sample volume and processing time while maintaining sensitivity. This achievement not only advanced fundamental biological research but also facilitated applications in drug discovery and biomarker screening. McQuary’s contributions remain a cornerstone in the evolution of lab-on-a-chip technologies, demonstrating a lasting impact on the field of bioengineering.