Mykhailo Kopylov

Papers

Total Citations

167

H-Index

About

Mykhailo Kopylov is a structural biology researcher whose work centers on advancing cryo-electron microscopy (cryo-EM) technology, with a particular focus on specimen preparation and workflow automation. His most significant contribution lies in the development and refinement of the Spotiton and Chameleon vitrification platforms — innovative robotic systems designed to address one of cryo-EM's most persistent challenges: the reliable preparation of vitrified specimens with optimal ice thickness. His 2020 paper on time-resolved cryo-EM using Spotiton has garnered 151 citations, underscoring its substantial influence on the field and demonstrating how this approach enables researchers to capture biological molecules in transient functional states. Beyond hardware innovation, Kopylov has contributed to the intelligent automation of cryo-EM preprocessing pipelines, helping reduce the manual decision-making burden that has historically slowed data collection workflows. His work on the Chameleon and Spotiton robots further illustrates a sustained commitment to making high-resolution structural biology more accessible, reproducible, and efficient. Collectively, his research represents a meaningful push toward fully streamlined cryo-EM, empowering structural biologists to resolve complex molecular machines with greater speed and confidence.