Nidhi Kundu

Papers

Total Citations

151

H-Index

About

Nidhi Kundu is a structural biologist whose work has advanced the frontiers of time-resolved cryo-electron microscopy (cryo-EM). Her research focuses on capturing dynamic biological processes at near-atomic resolution, with a particular emphasis on developing rapid mixing and sample deposition techniques. Kundu’s most notable contribution is her pioneering work on the Spotiton method, which enables time-resolved cryo-EM by rapidly mixing reactants and depositing samples onto grids within milliseconds. Her 2020 paper on this technique has garnered over 150 citations, reflecting its transformative impact on the field. By allowing researchers to visualize transient conformational states of macromolecular complexes—such as those involved in signaling or viral entry—Kundu’s innovations have opened new windows into understanding molecular mechanisms in real time. Her work bridges the gap between static structural snapshots and dynamic biological function, earning her recognition as a key figure in the next generation of cryo-EM methodology. For students and researchers, Kundu exemplifies how creative engineering and biological insight can together push the boundaries of what is observable in structural biology.