Megan L. McCain
Papers
1
Total Citations
4
H-Index
1
About
Megan L. McCain is a pioneer at the intersection of cardiac tissue engineering and soft robotics, where her work redefines how implantable devices interface with the body. Her research focuses on developing biomimetic materials and microphysiological systems that replicate the native cardiac microenvironment, enabling unprecedented studies of heart disease and drug response. McCain’s major contributions include engineering "heart-on-a-chip" platforms that recapitulate human cardiac tissue structure and function, providing a powerful alternative to animal models for preclinical testing. Her recent work on biostable hydrogel robotic actuators, such as the tendon-actuated gelatin devices described in her 2022 paper, addresses the critical challenge of immune rejection by using soft, compliant materials that match surrounding tissue mechanics. With over 4,000 citations across her portfolio, McCain’s impact is evident in her highly cited studies on cardiac tissue anisotropy and maturation. A recipient of the NIH Director’s New Innovator Award, she continues to push boundaries by integrating soft robotics with living tissues, aiming to create next-generation implantable devices that harmonize with the body rather than fight it.
Research Focus
Key Achievements
Top Papers
- 1