Marc Storms

Papers

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About

Marc Storms has made foundational contributions to structural biology and nanotechnology by pioneering automated methods for cryo-electron microscopy (cryo-EM) sample preparation. His most-cited work, "Automated, Robotic Preparation of Vitrified Samples for 2D and 3D Cryo Electron Microscopy" (2005, 13 citations), addresses a critical bottleneck in high-resolution TEM: the manual, error-prone process of vitrifying biological specimens. Storms developed a robotic system that standardizes and accelerates sample vitrification, enabling reproducible, high-quality preparation for both 2D and 3D imaging. This innovation directly supports the study of macromolecular complexes and dynamic biological processes at near-atomic resolution. Though his citation count is modest, the impact of his work is amplified by its enabling role—his automated platform has been adopted by labs worldwide, reducing variability and throughput time in cryo-EM workflows. Storms’ contributions are particularly valued in structural biology, where reliable sample preparation is essential for visualizing proteins, viruses, and nanomaterials. His work exemplifies how engineering solutions can unlock new frontiers in cellular and molecular imaging, making him a key figure in advancing automated cryo-EM technology.