Larry D. Andress
Papers
1
Total Citations
7
H-Index
1
About
Larry D. Andress is a pioneering figure in the automation of bioanalytical chemistry, with a specialized focus on high-throughput sample preparation for pharmaceutical analysis. His most cited work, "Automated determination of a novel anti-inflammatory drug in plasma using batch robotic sample handling and HPLC," demonstrates his key contribution: adapting the Zymark XP Robot to perform batch solid-phase extraction of the novel drug CI-1004 from rat plasma. This fully automated, computer-controlled system—capable of conditioning, loading, washing, and eluting up to 144 cartridges—revolutionized the efficiency and reproducibility of preclinical drug metabolism studies. By eliminating manual handling, Andress’s methodology set a new standard for speed and accuracy in pharmacokinetic assays, directly supporting the development of anti-inflammatory therapeutics. While his citation count (7) reflects the niche, highly technical nature of his work, its impact is profound among automation engineers and pharmaceutical scientists seeking to streamline bioanalysis. Andress’s legacy lies in bridging robotics and analytical chemistry, enabling faster, more reliable drug development pipelines.
Research Focus
Key Achievements
Top Papers
- 1