Linda A. Brunner
Papers
2
Total Citations
32
H-Index
2
About
Linda A. Brunner is a pioneer in the automation of bioanalytical chemistry, with a career dedicated to streamlining the complex processes of drug quantification in biological matrices. Her foundational work in the late 1980s and early 1990s introduced innovative, robot-assisted methods for sample preparation and chromatographic analysis, dramatically improving the efficiency and reproducibility of pharmacokinetic studies. Her most cited paper, "An Automated Method for the Determination of Diclofenac Sodium in Human Plasma" (1991, 23 citations), details a fully robotic system that aliquots samples, adds internal standards, and extracts compounds from acidified plasma, setting a new standard for high-throughput analysis. Earlier, her 1987 study on CGS 10787B (9 citations) demonstrated the integration of laboratory robotics with HPLC for simultaneous analysis of drug compounds in plasma and urine. Though her citation counts reflect a specialized niche, Brunner’s contributions were instrumental in advancing laboratory automation, reducing manual error, and accelerating drug disposition studies—a legacy that continues to influence modern bioanalytical workflows.
Research Focus
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Top Papers
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