B.K. Matuszewski
Papers
4
Total Citations
32
H-Index
3
About
B.K. Matuszewski is an analytical chemist whose research has made significant contributions to the field of bioanalytical method development, particularly in the quantitative determination of pharmaceutical compounds in human plasma. Specializing in high-performance liquid chromatography (HPLC) and automated sample preparation techniques, Matuszewski has pioneered the integration of robotic and semi-automated workflows to enhance the throughput and precision of drug analysis in biological matrices. Among his most notable contributions is the development of a semi-automated procedure for determining caspofungin — an important antifungal agent — in human plasma using solid-phase extraction and fluorescence detection, which has garnered 14 citations. His work has extended across a diverse range of clinically relevant compounds, including HMG-CoA reductase inhibitors such as simvastatin, the anti-asthmatic verlukast, and the antiparasitic drug ivermectin. By combining robotic sample processors with 96-well format extraction systems, Matuszewski's methodologies have helped standardize and accelerate pharmacokinetic studies in drug development settings. His body of work reflects a consistent commitment to improving analytical sensitivity, selectivity, and efficiency in pharmaceutical research, providing essential tools for clinical and preclinical investigators worldwide.
Research Focus
Key Achievements
Top Papers
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