Jian‐Zhang Pan
Papers
5
Total Citations
159
H-Index
5
About
Jian-Zhang Pan is an innovative researcher at the forefront of microfluidics, single-cell proteomics, and automated chemical synthesis. His work bridges cutting-edge engineering with biological and chemical discovery, developing transformative platforms that dramatically expand what is scientifically possible at the microscale. Pan's most celebrated contribution is the Pick-up Single-Cell Proteomic Analysis (PiSPA) workflow, which shattered previous barriers in single-cell proteomics by enabling the identification of up to 3,000 proteins per mammalian or tumor cell — triple the roughly 1,000-protein ceiling that had long limited the field. This breakthrough, which garnered 66 citations within a year of its 2024 publication, holds profound implications for cancer biology, drug discovery, and precision medicine. Equally impressive is his development of a roboticized, AI-assisted microfluidic system capable of executing up to 10,000 photocatalytic synthesis reactions per day, a feat that redefines throughput in organic chemistry. Pan has also advanced machine vision-guided rare cell sorting and fully automated nucleic acid analysis, demonstrating a remarkable ability to integrate robotics, artificial intelligence, and microfluidics into practical, high-impact tools. With nearly 160 total citations, his work is rapidly shaping the future of laboratory automation and single-cell biology.
Research Focus
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