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About

Dr. Hideki Enomoto is a leading figure in functional genomics, best known for his pivotal contributions to the FANTOM5 project, a landmark international consortium that systematically mapped transcription start sites across the human and mouse genomes. His most-cited work, the 2017 FANTOM5 paper (with over 360 citations), established a comprehensive atlas of promoter-level expression profiles using Cap Analysis of Gene Expression (CAGE) coupled with single-molecule sequencing. This resource, spanning nearly three thousand diverse samples, provided unprecedented, single-base-pair resolution of transcription initiation events, revolutionizing our understanding of gene regulation and promoter usage. Beyond this flagship achievement, Enomoto’s research has significantly advanced the study of transcriptional networks, particularly in the context of development and disease. His work has been instrumental in uncovering the complexity of non-coding RNAs and enhancer-derived transcripts. With a career marked by high-impact, collaborative science, Dr. Enomoto continues to shape the field of transcriptomics, offering the research community invaluable tools and datasets for decoding the regulatory logic of the genome.