G. Minesinger
Papers
2
Total Citations
9
H-Index
2
About
G. Minesinger is a pioneering researcher at the intersection of interventional oncology and therapeutic ultrasound, with a primary focus on advancing histotripsy—a non-invasive, non-thermal focused ultrasound technique that mechanically destroys tissue through cavitation. Their major contributions center on improving the precision and clinical viability of histotripsy through advanced image guidance, particularly using cone-beam computed tomography (CBCT). In their highly cited 2025 work, "Evaluation of targeting accuracy of cone beam CT guided histotripsy in an in vivo porcine model" (5 citations), Minesinger demonstrated the feasibility of performing targeted histotripsy treatments in the liver of healthy swine using a C-arm CBCT system calibrated to a robotic arm, achieving precise pseudotumor creation. Complementing this, their paper "Calibration correction to improve registration during cone-beam CT guided histotripsy" (4 citations) addresses a critical technical hurdle—improving the registration accuracy between the imaging and treatment systems to ensure reliable bubble cloud formation and tissue destruction. Together, these studies establish foundational protocols for translating histotripsy from the lab to the clinic, offering a radiation-free alternative to thermal ablation for liver tumors. Minesinger’s work is instrumental in making histotripsy a viable, non-ionizing option for cancer patients, with potential to revolutionize minimally invasive tumor treatment.
Research Focus
Key Achievements
Top Papers
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