Fang Jin
Papers
2
Total Citations
145
H-Index
2
About
Fang Jin is a pioneering researcher at the intersection of microfluidics and single-cell biology, whose work has fundamentally advanced the frontiers of digital molecular analysis and ultrasensitive proteomics. In a landmark 2016 study (79 citations), Jin introduced the **surface-assisted multifactor fluid segmentation (SAMFS)** approach, a transformative technique that enabled the automated generation of two-dimensional droplet arrays with tunable volumes. This innovation directly enabled multivolume digital PCR, providing a powerful, flexible platform for precise nucleic acid quantification with broad implications for diagnostics and genetic analysis. Building on this foundation, Jin’s most recent and highly impactful work (2024, 66 citations) tackles the grand challenge of single-cell proteomics. By developing the **pick-up single-cell proteomic analysis (PiSPA)** workflow, Jin shattered previous limitations, achieving the identification of up to 3,000 proteins from a single mammalian cell—a threefold improvement over existing shotgun methods. This breakthrough brings practical, high-coverage single-cell protein analysis within reach, opening new avenues for understanding cellular heterogeneity in health and disease. Through these innovations, Fang Jin has established herself as a leader in creating the microfluidic and analytical tools that are redefining the limits of molecular measurement.
Research Focus
Key Achievements
Top Papers
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- 2