Fabio Fazio
Papers
1
Total Citations
1,099
H-Index
1
About
Fabio Fazio has made pioneering contributions to the field of chemical glycobiology, with a particular focus on developing tools to decode the biological roles of complex carbohydrates. His most influential work introduced a revolutionary method for constructing printed covalent glycan microarrays, enabling high-throughput profiling of glycan-binding proteins. This seminal 2004 paper, with over 1,100 citations, established a standard platform for studying carbohydrate-protein interactions by coupling amine-functionalized glycans to amino-reactive glass slides. The array, featuring 200 synthetic and natural glycan sequences representing major glycoprotein structures, has become an essential resource for researchers investigating everything from pathogen recognition to immune system function. Fazio's innovation transformed the study of glycan-binding proteins by providing a robust, reproducible system for ligand discovery and specificity analysis. His work continues to underpin advances in vaccine development, diagnostics, and understanding of infectious diseases, cementing his reputation as a key architect of modern glycomics technology.
Research Focus
Key Achievements
Top Papers
- 1Printed covalent glycan array for ligand profiling of diverse glycan binding proteins1,099 citations · 2004