Christopher N. Scanlan
Papers
1
Total Citations
1,099
H-Index
1
About
Christopher N. Scanlan is a leading figure in glycobiology, whose work has fundamentally advanced our understanding of how glycans mediate immune recognition and pathogen interactions. His research centers on the structural and functional analysis of glycan-binding proteins, with a particular focus on the role of glycosylation in viral evasion and antibody neutralization. Scanlan’s most impactful contribution is the development of the printed covalent glycan array, a revolutionary platform described in his landmark 2004 paper (1,099 citations). This technology, which uses robotic printing to immobilize over 200 synthetic and natural glycan sequences, enabled high-throughput profiling of diverse glycan-binding proteins for the first time. Beyond this methodological breakthrough, his studies on the HIV envelope glycoprotein have been instrumental in revealing how dense glycan shields protect the virus from the immune system, informing vaccine design strategies. Scanlan’s work has not only provided critical tools for the glycobiology community but has also shaped our understanding of host-pathogen co-evolution, earning him recognition as a pioneer in the field.
Research Focus
Key Achievements
Top Papers
- 1Printed covalent glycan array for ligand profiling of diverse glycan binding proteins1,099 citations · 2004