Papers
9
Total Citations
684
H-Index
9
About
Ephrat Most is a prominent biomedical engineer and orthopedic biomechanics researcher whose work has fundamentally advanced our understanding of knee kinematics and total knee arthroplasty (TKA) design. Specializing in the biomechanical behavior of the knee at high flexion angles — a previously underexplored frontier — Most's research has directly informed the development of next-generation prosthetic designs aimed at restoring more natural joint function. Her most influential contributions examine cruciate ligament forces, tibial post impingement, and the kinematic performance of various TKA configurations under realistic muscle loading conditions. By employing sophisticated robotic testing systems, including a six-degree-of-freedom experimental platform she helped develop, Most generated highly reproducible in vitro data that revealed critical limitations in conventional prosthetic designs beyond 120 degrees of flexion. Her findings on posterior stabilized and cruciate-retaining implants have guided surgeons and engineers toward optimizing flexion outcomes for patients — a significant clinical challenge. With her most-cited papers accumulating hundreds of citations across the early 2000s and her work appearing consistently across key orthopedic biomechanics journals, Most's research has had a lasting and measurable impact on both surgical practice and implant engineering, making her a foundational voice in the field of knee reconstruction biomechanics.
Research Focus
Key Achievements
Top Papers
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- 3Kinematics of the knee at high flexion angles: An in vitro investigation94 citations · 2003
- 4Optimizing Flexion After Total Knee Arthroplasty86 citations · 2003
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- 7The Kinematics of Fixed- and Mobile-Bearing Total Knee Arthroplasty67 citations · 2003
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