David W. Holdsworth
Papers
4
Total Citations
26
H-Index
3
About
David W. Holdsworth is a leading figure in medical imaging and image-guided interventions, with research spanning preclinical robotics, 3D angiography, and joint kinematics. His most cited work, a 2010 study on integrating a needle-positioning robot with volumetric microcomputed tomography (microCT) for small animal stereotactic procedures (11 citations), demonstrates his pioneering contributions to high-precision preclinical research. By enabling oblique needle trajectories with sub-200-micrometer accuracy, this system allows targeted delivery of biological substances to rodent brains, advancing neuroscience and drug delivery studies. Holdsworth also developed techniques for registering needle-positioning robots to 3D ultrasound and CT (3 citations), enhancing image-guided interventions in small animals. His 2002 simulation of intra-operative 3D coronary angiography (10 citations) supports minimally invasive robotic cardiac surgery, while his 2012 work on measuring joint kinematics using single-perspective flat-panel radiography (2 citations) offers a safer, more accessible tool for studying joint function and pathology. With a career focused on bridging robotics, imaging, and clinical application, Holdsworth’s innovations have improved the accuracy and safety of interventions from the bench to the bedside.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3
- 4