Bilha Sandak
Papers
4
Total Citations
178
H-Index
4
About
Bilha Sandak is a computational biologist and structural bioinformatics researcher whose work has made significant contributions to the field of molecular docking and biomolecular recognition. Her research focuses on developing algorithms and computational methods for modeling protein-ligand interactions, with particular emphasis on flexible docking techniques that account for the dynamic nature of biological molecules. Sandak's most influential work, "Flexible Docking Allowing Induced Fit in Proteins" (1998, 120 citations), introduced a groundbreaking approach that mimics induced fit in molecular recognition by permitting hinge-bending domain movements during docking simulations — a critical advancement that brought computational models closer to biological reality. Her earlier paper on automated computer vision and robotics-based techniques for 3D flexible biomolecular docking (1995, 46 citations) demonstrated her innovative cross-disciplinary approach, bridging robotics, computer vision, and structural biology to tackle the complex problem of molecular surface recognition. Her sustained focus on conformationally flexible protein docking has helped lay important groundwork for rational drug design, offering computational tools that better reflect how molecules actually behave during binding events in living systems.
Research Focus
Key Achievements
Top Papers
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- 3Docking of conformationally flexible proteins8 citations · 1996
- 4