Bilha Sandak

Weizmann Institute of Science, Tel Aviv University

Papers

4

Total Citations

178

H-Index

4

About

Bilha Sandak is a computational biologist and structural bioinformatics researcher whose work has made significant contributions to the field of molecular docking and biomolecular recognition. Her research focuses on developing algorithms and computational methods for modeling protein-ligand interactions, with particular emphasis on flexible docking techniques that account for the dynamic nature of biological molecules. Sandak's most influential work, "Flexible Docking Allowing Induced Fit in Proteins" (1998, 120 citations), introduced a groundbreaking approach that mimics induced fit in molecular recognition by permitting hinge-bending domain movements during docking simulations — a critical advancement that brought computational models closer to biological reality. Her earlier paper on automated computer vision and robotics-based techniques for 3D flexible biomolecular docking (1995, 46 citations) demonstrated her innovative cross-disciplinary approach, bridging robotics, computer vision, and structural biology to tackle the complex problem of molecular surface recognition. Her sustained focus on conformationally flexible protein docking has helped lay important groundwork for rational drug design, offering computational tools that better reflect how molecules actually behave during binding events in living systems.

Research Focus

Key Achievements

4
H-Index
4
Papers
178
Total Citations
45
Avg Citations/Paper
🏆 Most Cited Paper
Flexible docking allowing induced fit in proteins: Insights from an open to closed conformational isomers
120 citations · 1998
📈 Most Prolific Year: 1998 (2 Papers)
🤝 Key Collaborators: 2
🏛 Institutions: Weizmann Institute of Science, Tel Aviv University

Top Papers

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Key Collaborators

Contact & Links

Available for collaboration
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