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Anna Ehrlund is a leading figure in functional genomics, best known for her pivotal contributions to the FANTOM5 consortium, where she helped revolutionize our understanding of gene regulation. Her primary research focuses on transcriptional initiation, promoter architecture, and the application of Cap Analysis of Gene Expression (CAGE) to map the human and mouse transcriptomes at single-base resolution. Ehrlund’s most cited work, the landmark 2017 paper “FANTOM5 CAGE profiles of human and mouse samples,” has garnered over 360 citations, reflecting its foundational role in defining transcription start sites across thousands of diverse biological samples. This massive collaborative effort not only provided an unprecedented atlas of promoter usage but also enabled the systematic identification of enhancer RNAs and non-coding transcription. Beyond this flagship study, Ehrlund’s research has advanced our understanding of tissue-specific gene expression and the regulatory logic underlying cellular identity. Her work stands as a cornerstone for researchers studying transcriptional regulation, epigenomics, and the functional annotation of mammalian genomes, making her a key architect of modern transcriptome mapping.