Alexander E. Marras
Papers
6
Total Citations
273
H-Index
5
About
Alexander E. Marras is a pioneering researcher at the intersection of DNA nanotechnology, molecular robotics, and nanomechanics. His work centers on harnessing the programmable self-assembly properties of DNA origami to engineer functional nanostructures and nanomachines capable of complex, controlled motion — a challenge that has long constrained the field. Marras's most influential contribution, "DNA Origami Compliant Nanostructures with Tunable Mechanical Properties" (2013, 137 citations), fundamentally advanced the field by demonstrating that DNA origami structures need not be rigidly static, opening the door to mechanically flexible nanoscale devices. Building on this foundation, his 2018 work on cation-activated avidity (76 citations) introduced a novel actuation strategy enabling rapid reconfiguration of DNA nanodevices without traditional strand-displacement methods — a significant leap for nanomanufacturing and drug delivery applications. His paper-origami-inspired approach to DNA nanomachine design (2018, 40 citations) further expanded the motion repertoire available to molecular engineers. Throughout his career, Marras has consistently applied kinematic design principles to DNA origami, bridging mechanical engineering concepts with molecular biology. His cumulative body of work has garnered over 270 citations, establishing him as a creative and technically rigorous voice shaping the future of molecular-scale robotics.
Research Focus
Key Achievements
Top Papers
- 1DNA Origami Compliant Nanostructures with Tunable Mechanical Properties137 citations · 2013
- 2Cation-Activated Avidity for Rapid Reconfiguration of DNA Nanodevices76 citations · 2018
- 3
- 4
- 5Design and Fabrication of DNA Origami Mechanisms and Machines8 citations · 2012
- 6