Susanne Unger
Papers
1
Total Citations
19
H-Index
1
About
Susanne Unger is an immunologist whose research focuses on the intricate mechanisms of adaptive immunity, particularly in the context of primary immunodeficiencies and chronic viral infections. Her work has significantly advanced our understanding of T cell dysfunction in common variable immunodeficiency (CVID), a disorder characterized by impaired antibody production and recurrent infections. In her most-cited study, "Exhausted phenotype of follicular CD8 T cells in CVID" (2020, 19 citations), Unger identified a novel exhausted state in follicular CD8 T cells, revealing how chronic immune activation drives functional impairment in CVID patients. This discovery provides critical insights into the pathogenesis of CVID and opens potential therapeutic avenues for restoring T cell function. Beyond this landmark paper, Unger’s contributions have illuminated the interplay between T cell exhaustion and B cell help, offering a deeper understanding of immune dysregulation. Her work, though early in its citation impact, has already been recognized for its translational relevance, bridging basic immunology with clinical applications. Unger’s research continues to shape the field, making her a rising voice in the study of immune exhaustion and primary antibody deficiencies.
Research Focus
Key Achievements
Top Papers
- 1Exhausted phenotype of follicular CD8 T cells in CVID19 citations · 2020