Adam Klocperk
Papers
1
Total Citations
19
H-Index
1
About
Adam Klocperk is a clinical immunologist whose research centers on the intricate mechanisms of immune dysregulation, with a particular focus on common variable immunodeficiency (CVID) and T-cell biology. His most cited work, "Exhausted phenotype of follicular CD8 T cells in CVID" (2020), has garnered 19 citations, marking a significant contribution to understanding how chronic antigenic stimulation drives T-cell exhaustion in this primary immunodeficiency. This study illuminated a novel pathway of immune dysfunction, revealing that follicular CD8 T cells in CVID patients exhibit an exhausted phenotype, which may underpin the impaired antibody responses and increased infection susceptibility seen in the disease. Klocperk’s work bridges fundamental immunology and clinical application, offering potential targets for therapeutic intervention. His research has been instrumental in characterizing the cellular and molecular underpinnings of CVID, a condition affecting thousands worldwide. With a growing citation impact, Klocperk continues to advance the field, providing insights that could lead to improved diagnostics and treatments for patients with complex immune disorders.
Research Focus
Key Achievements
Top Papers
- 1Exhausted phenotype of follicular CD8 T cells in CVID19 citations · 2020