Mauro Perretti

Papers

Total Citations

194

H-Index

About

Mauro Perretti is a leading figure in inflammation pharmacology, renowned for pioneering the study of pro-resolving mediators and their therapeutic potential. His research centers on the cellular and molecular mechanisms that control the resolution of inflammation, with a particular focus on neutrophil biology and microparticles. A key contribution is his work on the heterogeneity of neutrophil microparticles, as demonstrated in his highly cited 2013 study (194 citations), which revealed distinct proteomes and functional properties, fundamentally altering our understanding of how these vesicles influence vascular and inflammatory diseases. This work has helped shift the paradigm from simply blocking inflammation to actively promoting its resolution. With a career spanning over two decades, Perretti’s impact is underscored by his numerous high-impact publications and his role in identifying novel pathways, such as those mediated by annexin A1 and formyl peptide receptors. His findings have opened new avenues for developing therapeutics that harness the body’s own resolution mechanisms, making him a pivotal researcher for students and scientists interested in the next generation of anti-inflammatory treatments.