Papers
2
Total Citations
82
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About
KD Derr has made pivotal contributions to structural biology, particularly in the high-throughput analysis of membrane proteins. Their research focuses on developing automated electron microscopy strategies to accelerate the screening of two-dimensional crystallization trials—a critical bottleneck in determining membrane protein structures. Derr’s 2007 paper, “A high-throughput strategy to screen 2D crystallization trials of membrane proteins,” has garnered 44 citations, establishing a foundational method that reduces manual labor and increases experimental throughput. Building on this, their 2010 work, “Automated electron microscopy for evaluating two-dimensional crystallization of membrane proteins,” with 38 citations, refined these techniques by integrating automated image acquisition and analysis, enabling more reliable and rapid assessment of crystal quality. Together, these contributions have streamlined the path to high-resolution structures of challenging membrane proteins, impacting fields from drug discovery to bioenergetics. Derr’s work exemplifies how engineering and automation can transform traditional structural biology workflows, making them accessible to a broader research community. Their achievements underscore a career dedicated to overcoming technical hurdles in membrane protein crystallography.
Research Focus
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