David L. Stokes
RTI International, New York Structural Biology Center, New York University
Papers
5
Total Citations
168
H-Index
5
About
David L. Stokes has made significant contributions across two distinct but equally impactful scientific domains: nanoscale thermoelectric materials and structural biology of membrane proteins. In the realm of energy science, his 2007 work on thermoelectric devices utilizing nanoscale materials — including superlattices and self-assembled quantum dots — advanced the field of energy harvesting for electronics, garnering 58 citations and establishing him as a contributor to sustainable energy solutions. The majority of his most-cited work, however, centers on membrane protein structural biology, where he pioneered high-throughput and automated approaches to two-dimensional crystallization — a notoriously challenging bottleneck in determining membrane protein structures. His 2007 screening strategy paper (44 citations) and subsequent 2010 works on automated electron microscopy pipelines (38 and 23 citations respectively) dramatically accelerated the pace at which researchers could pursue structural insights into this critically important class of proteins, which serve as drug targets for numerous diseases. His 2012 review of high-throughput electron crystallography methods further cemented his role as a methodological innovator. Stokes's career reflects a rare versatility, with meaningful impact in both materials science and structural biology.
Research Focus
Key Achievements
Top Papers
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- 4An automated pipeline to screen membrane protein 2D crystallization23 citations · 2010
- 5High-Throughput Methods for Electron Crystallography5 citations · 2012