Jeroen Molenaar
Papers
2
Total Citations
12
H-Index
2
About
Jeroen Molenaar is a researcher whose work sits at the intersection of biophysical screening technologies and fragment-based drug discovery. His most recognized contributions center on the application of nano-Differential Scanning Fluorimetry (nano-DSF), a sophisticated thermal shift assay technique used to evaluate how a target protein's melting temperature responds to changes in its molecular environment. This methodology has proven particularly valuable in the early stages of drug development, where identifying promising molecular fragments that interact with disease-relevant proteins is a critical and often challenging step. Molenaar's 2021 work on nano-DSF for fragment-based lead discovery has garnered citation attention within the structural biology and medicinal chemistry communities, reflecting growing interest in more sensitive and efficient biophysical screening platforms. By helping to establish and validate the utility of nano-DSF in this context, his research contributes to accelerating the pipeline from initial fragment hits to viable therapeutic leads. Though still building his citation profile, Molenaar's focus on precise, label-free protein stability measurements positions him as a thoughtful contributor to the evolving toolkit available to researchers working in early-stage drug discovery and protein biochemistry.
Research Focus
Key Achievements
Top Papers
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- 2