James Foadi

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About

James Foadi is a structural biologist whose research centers on macromolecular crystallography (MX), with a particular focus on advancing experimental phasing methods for determining protein structures. His major contribution lies in pioneering high-throughput *in situ* experimental phasing, a technique that leverages automated robotics and multi-crystal frameworks at synchrotrons to dramatically reduce human intervention. This innovation, detailed in his most-cited 2020 paper (6 citations), streamlines the traditionally labor-intensive process of solving novel protein structures, enabling faster and more efficient data collection from hundreds of microcrystals. Foadi’s work is pivotal for structural genomics and drug discovery, where rapid structure determination is critical. Beyond this, he has contributed to the development of software tools for crystallographic data analysis, enhancing reproducibility in the field. His achievements reflect a commitment to automating and scaling MX workflows, making synchrotron-based structure solution more accessible to the broader research community.