Amanda R. Smolock
Papers
3
Total Citations
181
H-Index
3
About
Amanda R. Smolock is a pioneering researcher in the field of noninvasive, nonthermal ablation technologies, with a primary focus on robotically assisted sonic therapy (RAST) for targeted tissue destruction. Her work centers on histotripsy, a novel focused ultrasound technique that mechanically fractionates tissue without heat, offering a safer alternative for tumor treatment. Smolock’s major contributions include the first proof-of-concept study demonstrating RAST’s feasibility for creating clinically relevant hepatic ablations in a porcine model, capable of treating 2-cm liver tumors (90 citations). She further validated this approach for renal ablation (47 citations) and developed modified pulse sequences to mitigate body wall damage during hepatic procedures (44 citations). These studies collectively establish RAST as a promising modality for noninvasive cancer therapy, with potential to reduce complications associated with thermal ablation. Her work has garnered significant attention, with her most-cited paper accumulating 90 citations, underscoring its impact on advancing nonthermal ablation research. Smolock’s innovative contributions are paving the way for clinical translation of histotripsy, positioning her as a key figure in the evolution of image-guided, robot-assisted therapies for solid organ tumors.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3