Papers
2
Total Citations
70
H-Index
2
About
Dr. Warren Casey is a leading figure in the advancement of in vitro toxicology, dedicated to replacing, reducing, and refining the use of animals in chemical safety testing. His primary research focuses on the development and validation of high-throughput screening (HTS) assays and computational models to predict human toxicity. Dr. Casey’s major contributions include pioneering the use of robotic systems for endocrine disruptor screening, most notably through his work on the MCF-7:WS8 cell proliferation assay (21 citations), which enables the rapid detection of estrogenic and anti-estrogenic activity. He is also a key voice in the strategic implementation of these technologies, as highlighted in his highly cited 2023 review on the accomplishments and future directions of HTS in toxicology (49 citations). By championing a shift from traditional, low-throughput animal studies to modern, mechanism-based approaches, Dr. Casey’s work is fundamentally reshaping how regulatory agencies and pharmaceutical companies evaluate chemical safety, making the process faster, more human-relevant, and more cost-effective.
Research Focus
Key Achievements
Top Papers
- 1
- 2