Chun Yang
Papers
2
Total Citations
28
H-Index
2
About
Chun Yang’s research advances the critical field of endocrine toxicology, with a focus on developing automated, high-throughput bioassays to detect endocrine-disrupting chemicals (EDCs). Their major contributions include pioneering robotic platforms for screening estrogenic and anti-estrogenic activity, which are essential for identifying compounds that may pose risks to human health. Yang’s most cited work, “A Robotic MCF-7:WS8 Cell Proliferation Assay to Detect Agonist and Antagonist Estrogenic Activity” (2013, 21 citations), established a reliable, robotized method to evaluate 78 test substances for their potential to mimic or block estrogen—a key step in assessing chemical safety. This work is complemented by “A robotic BG1Luc reporter assay to detect estrogen receptor agonists” (2014, 7 citations), which further refined detection of estrogen receptor agonists. By integrating robotics into cell-based assays, Yang has enhanced reproducibility and throughput, enabling more efficient screening of environmental contaminants and pharmaceuticals. Their research directly supports regulatory toxicology and public health efforts to mitigate EDC exposure, making Yang a notable contributor to the development of alternative testing methods that reduce reliance on animal models.
Research Focus
Key Achievements
Top Papers
- 1
- 2A robotic BG1Luc reporter assay to detect estrogen receptor agonists7 citations · 2014