Matthew Stoner
Papers
2
Total Citations
28
H-Index
2
About
Matthew Stoner is a pioneering researcher in the development of high-throughput, robotic bioassays for detecting endocrine-disrupting chemicals (EDCs). His work centers on creating automated, cell-based screening platforms to identify compounds with estrogenic activity (EA) or anti-estrogenic activity (AEA), which are critical for assessing potential adverse health effects from environmental and pharmaceutical substances. Stoner’s major contribution lies in engineering robotized assays that replace manual, time-consuming procedures, enabling rapid and reproducible screening of large chemical libraries. His most cited paper, “A Robotic MCF-7:WS8 Cell Proliferation Assay to Detect Agonist and Antagonist Estrogenic Activity” (2013, 21 citations), demonstrates a fully automated system using MCF-7:WS8 cells to evaluate 78 test substances for EA and AEA, significantly advancing toxicological testing efficiency. A subsequent study, “A robotic BG1Luc reporter assay to detect estrogen receptor agonists” (2014, 7 citations), further refines this approach by incorporating a luciferase reporter gene for sensitive, high-throughput detection of estrogen receptor agonists. Stoner’s innovations have streamlined EDC screening, reducing human error and increasing throughput, making his work foundational for regulatory toxicology and environmental health research. His robotic platforms continue to influence modern assay development, offering a scalable solution for chemical safety assessment.
Research Focus
Key Achievements
Top Papers
- 1
- 2A robotic BG1Luc reporter assay to detect estrogen receptor agonists7 citations · 2014