G. J. Kollessery
Papers
1
Total Citations
21
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1
About
G. J. Kollessery is a pioneering researcher in environmental toxicology and endocrine disruption, with a specialized focus on developing high-throughput robotic bioassays for detecting hormonal activity. Their most cited work, "A Robotic MCF-7:WS8 Cell Proliferation Assay to Detect Agonist and Antagonist Estrogenic Activity" (2013), has garnered 21 citations and represents a major methodological contribution to the field. This study introduced an automated, robotized assay using MCF-7:WS8 cell lines to screen 78 test substances for estrogenic (EA) and anti-estrogenic (AEA) activity, addressing critical concerns about endocrine-disrupting chemicals in the environment. Kollessery’s innovation lies in transforming a traditional, labor-intensive cell proliferation assay into a reproducible, high-throughput robotic platform, enabling more efficient detection of potential endocrine disruptors. This work has significant implications for regulatory toxicology and environmental health, providing a reliable tool for screening chemicals that may adversely affect human health. By bridging robotics with cellular toxicology, Kollessery has advanced the precision and scalability of endocrine activity testing, making their research foundational for subsequent studies on chemical safety and risk assessment.
Research Focus
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Top Papers
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